Prostate Cancer Clinical Trials & Research

Prostate patients are carefully monitored by physicians and prostate cancer researchers throughout the clinical trial.

Prostate cancer clinical trials are used to determine just how effective promising new therapies can be. Although they are often thought of as experimental studies, clinical trials are actually conducted after a treatment has been deemed safe. Patients are carefully monitored by physicians and prostate cancer researchers throughout the entire process. Patients are never obligated to participate, and can end their participation at any time.

Is a Clinical Trial the Right Option for Your Prostate Cancer Treatment?

Clinical trials are not only safe and carefully regulated, but also an important step in determining how a new treatment can best be used to help patients. During a clinical trial, investigators will learn:

  • Which doses of the treatment are most effective
  • Which patients respond best to the treatment (e.g., patients with a certain stage of cancer, or patients whose tumors are made up of a certain kind of cells)
  • Whether the treatment provides the best results on its own or when combined with other therapies
  • What side effects might occur, and how they can be managed

As a National Cancer Institute-designed Comprehensive Cancer Center, Moffitt Cancer Center is constantly conducting clinical trials to study the newest treatments for prostate cancer. For instance, we have investigated the role of hormone therapy in patients with rising prostate-specific antigen (PSA) levels after their first attempt at treatment, as well as the effectiveness of bone-strengthening therapies to help reduce the likelihood that prostate cancer will spread to the bones. These are just a small sampling of the trials we’ve conducted; we continually strive to offer our patients more effective treatment options, and our robust clinical trials program is one of the main ways we are able to do so.

To learn more about our prostate cancer clinical trials, call  1-813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form online. No referral is required; our clinical trial navigators will be happy to help you find a trial that may suit your treatment goals.

Click Here to View Clinical Trials

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Open Clinical Trials:

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CLINICAL TRIAL 19137

A Randomized Phase II Trial of Abiraterone, Olaparib, or Abiraterone + Olaparib in Patients with Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

Disease Site: Prostate

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CLINICAL TRIAL 20056

Phase II Clinical Trial of Green Tea Catechins in Men on Active Surveillance (AS)

Disease Site: Prostate

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CLINICAL TRIAL 20377

A Phase 2 Multicohort Study of Nivolumab in Combination with Docetaxel and Androgen Deprivation Therapy in Metastatic Hormone Sensitive Prostate Cancer Patients with DNA Damage Repair Defects or Inflamed Tumors

Disease Site: Prostate

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CLINICAL TRIAL 20628

A Phase II, Open-Label, Study to Assess the Efficacy, Safety, and Tolerability of AZD4635 in Combination with Durvalumab and in Combination with Cabazitaxel and Durvalumab in Patients Who Have Progressive Metastatic Castrate-Resistant Prostate Cancer (AARDVARC)

Disease Site: Prostate

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CLINICAL TRIAL 18523

A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African American Men with Prostate Cancer (VANDAAM Study)

Disease Site: Prostate

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CLINICAL TRIAL 20010

IRONMAN: International Registry for Men with Advanced Prostate Cancer

Disease Site: Prostate

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CLINICAL TRIAL 20094

EDRN Prostate MRI Biomarker Study and Reference Set

Disease Site: Prostate

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