Cancer Type: Malignant Hematology
Study Type: Treatment
Phase: Phase I
Principal Investigator: Sweet, Kendra
A Phase 1, Multi-center, Open-label Study of IMGN632 Administered Intravenously in Patients with Relapsed/Refractory CD123-positive Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies
The purpose of this study is to determine the Maximum Tolerated Dose (MTD) and assess the safety, tolerability, PK, immunogenicity, and preliminary anti-leukemia activity of IMGN632 when administered as monotherapy to patients with CD123+ disease.
To determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of IMGN632 on the selected dosing schedule(s) (dose escalation) To assess the anti-leukemia activity in BPDCN patients (tumor-specific expansion cohort)
If you are interested in learning more about clinical trials, our clinical trial navigators can discuss your options and recommend opportunities that may be suitable for you. Call 813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.
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