Randomized Trial of Prolonged Use of Negative Pressure Wound Therapy in Patients Undergoing Surgical Procedures for the Management of Gastrointestinal Malignancies
This randomized trial will use a Negative Pressure Wound Therapy device or standard wound closure, in participants with gastrointestinal neoplasms, to measure the rate of surgical site infections
This study proposes to estimate the effectiveness of prolonged use (7 days) of NPWT in an oncologic setting. We plan to address the following aims: 1) To estimate the effectiveness rate of the NPWT dressing in decreasing wound infection for oncologic gastrointestinal surgical procedures; 2) To evaluate if usage of NPWT is associated with earlier return to intended oncologic therapy (RIOT) after surgical resections for gastrointestinal cancer; and 3) To test the difference in SSI between standard wound therapy versus NPWT in decreasing wound events after oncologic gastrointestinal procedure. We hypothesize use of the negative pressure dressing could decrease the incidence of postoperative infection complication (SSI) and possibly lead to faster initiation of antineoplastic therapy.
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