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Andrew Kuykendall, MD

 
Specialty: Hematology/Oncology
Program: Malignant Hematology

Overview

Cancer Focus: Leukemia, Myelodysplastic Syndromes (MDS)

      Dr. Kuykendall is an Assistant Member at Moffitt Cancer Center in the Department of Malignant Hematology. He earned his MD from University of Florida College of Medicine and completed an Internal Medicine residency at the University of South Florida and a subsequent Hematology and Medical Oncology fellowship at Moffitt Cancer Center/University of South Florida. He primarily focuses his clinical and research efforts on myeloproliferative neoplasms (MPNs), MDS/MPN overlap syndromes and systemic mastocytosis (SM) where he is dedicated to developing novel, disease-modifying therapies for these rare diseases.  He is the primary investigator of numerous clinical trials and an active member of the MPN-Research Consortium – a collaborative effort aimed at improving therapeutic options for MPN patients by rationally and efficiently developing disease-modifying therapies.      


Education & Training

Fellowship:

  • University of South Florida at Moffitt Cancer Center - Hematology and Medical Oncology

Residency:

  • University of South Florida - Internal Medicine

Medical School:

  • University of Florida College of Medicine - M.D.
Participating Trials

CLINICAL TRIAL 20600
A Phase I, Open-Label, Multicenter, Dose Escalation, Dose Expansion Study of PRT543 in Patients with Advanced Solid Tumors and Hematologic Malignancies
Condition: Malignant Hematology
Intervention: Jakafi (Ruxolitinib); PRT543 (); Ruxolitinib ()
Open

CLINICAL TRIAL 20634
A Randomized, Double-Blind, Phase 3 Study to Evaluate the Activity of Momelotinib (MMB) versus Danazol (DAN) in Symptomatic, Anemic Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera (PV)Myelofibrosis, or Post Essential Thrombocythemia (ET) Myelofibrosis who were Previously Treated with JAK Inhibitor Therapy
Condition: Malignant Hematology
Intervention: Danazol (); Momelotinib (); Momelotinib/Danazol/Placebo ()
Open

If you believe you are eligible for one of these trials or studies, please call
813-745-6100 or toll-free 1-800-679-0775.

Publications

  • Talati C, Dhulipala VC, Extermann M, Al Ali N, Kim J, Komrokji R, Sweet K, Kuykendall A, Sehovic M, Reljic T, Djulbegovic B, Lancet JE. Comparisons of commonly used front-line regimens on survival outcomes in patients aged 70 years and older with acute myeloid leukemia. Haematologica. 2020 Jan.105(2):398-406. Pubmedid: 31073071. Pmcid: PMC7012500.
  • Kuykendall AT, Horvat NP, Pandey G, Komrokji R, Reuther GW. Finding a Jill for JAK: Assessing Past, Present, and Future JAK Inhibitor Combination Approaches in Myelofibrosis. Cancers (Basel). 2020 Aug.12(8). Pubmedid: 32823910. Pmcid: PMC7464183.
  • Kuykendall AT, Padron E. Treatment of MDS/MPN and the MDS/MPN IWG International Trial: ABNL MARRO. Curr Hematol Malig Rep. 2019 Dec.14(6):543-549. Pubmedid: 31776774.
  • Kuykendall A, Duployez N, Boissel N, Lancet JE, Welch JS. Acute Myeloid Leukemia: The Good, the Bad, and the Ugly. Am Soc Clin Oncol Educ Book. 2018 May.38:555-573. Pubmedid: 30231330.
  • Kuykendall AT, Shah S, Talati C, Al Ali N, Sweet K, Padron E, Sallman DA, Lancet JE, List AF, Zuckerman KS, Komrokji RS. Between a rux and a hard place: evaluating salvage treatment and outcomes in myelofibrosis after ruxolitinib discontinuation. Ann Hematol. 2018 Mar.97(3):435-441. Pubmedid: 29189896.
  • Kuykendall AT, Talati C, Al Ali N, Sweet K, Padron E, Sallman DA, Lancet JE, List AF, Zuckerman KS, Komrokji RS. The Treatment Landscape of Myelofibrosis Before and After Ruxolitinib Approval. Clin Lymphoma Myeloma Leuk. 2017 Dec.17(12):e45-e53. Pubmedid: 28869184.
  • Kuykendall A, Chiappori A. Advanced EGFR mutation-positive non-small-cell lung cancer: case report, literature review, and treatment recommendations. Cancer Control. 2014 Jan.21(1):67-73. Pubmedid: 24357744.
  • Budzevich M, Dilling T, Zhang G, Kuykendall C, Moros E. SU-E-J-167: Optimal Number of Respiratory Phases in 4D PET for Radiotherapy Planning: Motion-Simulated Phantom Study. Med Phys. 2012 Jun.39(6Part8):3691. Pubmedid: 28518903.

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