Molecular Oncology in the News

Joseph Kissil, Vice-Chair

June 2021

  • New Grant Award: Mark G. Alexandrow, PhD received a notice of award from the NIH for an R01 grant to study the roles of Rb and Myc in directly controlling enzymatic activity of the replicative CMG helicase. Damon Reed, MD, is a collaborator on the project.
  • Jennifer Binning, PhD, received a notice of award from the NIH for an R35 MIRA grant to study the molecular details governing deglycation and protein repair.
  • New Grant Award: Ana P. Gomes, PhD, received an Innovation Award from the American Lung Association to study age-related mechanisms of drug resistance in non-small cell lung cancer.
  • New Grant Award: Ana P. Gomes, PhD, received a Scientific Research Grant from the Florida Breast Cancer Foundation to evaluate NAD+ Kinase’s role in metastatic triple negative breast cancer.
  • New Grant Award: Ana P. Gomes, PhD, in collaboration with Gina DeNicola, PhD and Stephen Gardell, PhD (Advent Health) received a Bankhead-Coley Cancer Research Award from the State of Florida to study the role of aging and pyridine nucleotides in non-small cell lung cancers.
  • New Publication: Wright GM, Gimbrone NT, Sarcar B, Percy TR, Gordián ER, Kinose F, Sumi NJ, Rix U, Cress WD. CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines. PLoS One. 2021;16(6):e0252927. Epub 2021/06/18. doi: 10.1371/journal.pone.0252927. PubMed PMID: 34138895.
  • New Publication: Ana P. Gomes, PhD, co-lead a study describing how NAD+ kinase is regulated by oncogenic KRAS to sustain de novo NADP+ production in pancreatic ductal adenocarcinoma. “NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma”. Cell Rep. 2021 Jun 15;35(11):109238. PMID: 34133937
  • New Trainee: Stanislav Drapela, PhD joins the Gomes Lab as a postdoctoral fellow.

May 2021

  • New Grant Award: Florian Karreth, PhD received a notice of award from the NIH for an R01 grant focused on chromosome 1q ceRNAs in melanoma progression and metastasis.
  • New Publication: Florian Karreth, PhD, co-authored a study lead by Keiran Smalley, PhD and Jane Messina, MD describing mutations found in acral nevi. "A Mutational Survey of Acral Nevi”. JAMA Dermatol. 2021 May 12. PMID: 33978681
  • Nicol Mecozzi, Research Associate in the Karreth lab submitted a preprint to bioRxiv titled "Genetic Tools for the Stable Overexpression of Circular RNAs." doi: https://doi.org/10.1101/2021.05.27.446018
  • Ana P. Gomes, PhD, presented at the 2020 AACR Annual Meeting at the Educational Session: Understanding Mechanisms of Aging in Cancer Development in Human Populations.
  • New Trainee: Devesh Raizada, a graduate student in the Moffitt-USF Cancer Biology Ph.D. Program, selects Ana P. Gomes, PhD, as his major professor and joins the Gomes Lab.

April 2021

  • New Publication: Olga Vera, PhD, Postdoctoral Fellow in the Karreth lab published an article titled "A MAPK/miR-29 Axis Suppresses Melanoma by Targeting MAFG and MYBL2." Cancers. 2021 Mar 19. PMID: 33808771
  • Ana P. Gomes, PhD, was selected as a Rising Star of Cancer Metabolism and Signaling by the New York Academy of Sciences.
  • New Trainee: Joanne Tejero, a graduate student in the USF Molecular Medicine Ph.D. Program, selects Ana P. Gomes, PhD, as her major professor and joins the Gomes Lab.

March 2021

  • Faculty: Joseph (Joe) Kissil, PhD joins the department as Vice-chair and Senior Member, Moffitt Distinguished Scholar, and Co-Leader of the Cancer Biology & Evolution Program. Welcome, Dr. Kissil!
  • New Grant: Elsa Flores, PhD, received notification that a P01 focused on Lung Cancer Metabolism will receive funding. Dr. Flores is the contact PI, co-Director of the Administrative Core, and Leader of Project 1. Doug Cress, PhD, and Florian Karreth, PhD, will serve a co-Directors of the Pre-Clinical Core. John Koomen, PhD, will serve as Director of the Proteomics and Metabolism Core.
  • Suman Govindaraju, PhD, Postdoctoral Fellow in the K. Mann Lab, was selected for an Oral Presentation at the upcoming 2021 Moffitt Scientific Symposium.
  • New Patent: Mark G. Alexandrow, PhD is named inventor for Provisional Patent submission #63/157,268 “Helicase Inhibitors for the Treatment of Cancers”. Identified first-in-class inhibitors of HPV16/18/31 E1 helicases.
  • New Trainee: Amanda Meshey, graduate student in the Moffitt-USF Cancer Biology Ph.D. Program, selects Michael Mann, PhD, as her major professor and joins the M. Mann Lab.

February 2021

  • New Grant Award: Gary W. Reuther, PhD received a notice of award from the NIH for an R01 grant to study the role of SHP2 in JAK2 inhibitor persistence in myeloproliferative neoplasms.
  • New Publication: Gary W. Reuther, PhD co-authored work from a Moffitt team science collaboration with the labs of Nicholas Lawrence and Ernst Schönbrunn (Drug Discovery) reporting the Schönbrunn lab’s determination of the first-ever co-crystal structures of two FDA-approved JAK2 inhibitors for myeloid neoplasms, ruxolitinib and fedratinib, with the kinase domain of JAK2. “Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof”. J Med Chem. 2021 Feb 11. PMID: 33570945.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Solanki HS, Welsh EA, Fang B, Izumi V, Darville LNF, Stone B, Franzese R, Chavan S, Kinose F, Imbody D, Koomen JM, Rix U, Haura EB. Cell-type Specific Adaptive Signaling Responses to KRASG12C inhibition. Clin Cancer Res. 2021 Feb 22:clincanres.CCR–20–3872-A.2020. Online ahead of print. PMID: 33619172.
  • New Trainee: Rahim Ullah, PhD, joins the Lixin Wan Lab as a Postdoctoral Fellow.
  • New Trainee: Oscar Ospina, PhD, was appointed to the T32 Training Program in Cancer Biology and Data Science.
  • New Publication: Ana Gomes, PhD wrote an Authors’ view piece in Molecular & Cellular Oncology: Age-induced metabolic reprogramming underlies cancer progression.
  • New Publication: Florian Karreth, PhD, co-authored a perspective on the future of animal models in melanoma research in Cancer Cell. This paper, titled "Melanoma models for the next generation of therapies", is the result of a workshop on melanoma models organized by the Melanoma Research Alliance.
  • New Trainee: Nicol Mecozzi, Research Associate in the Karreth lab, was admitted to the Moffitt/USF Cancer Biology PhD program.
  • Neel Jasani, graduate student in the Moffitt-USF Cancer Biology Ph.D. Program in the Karreth lab, won a Best Poster Award at the University of South Florida’s Health Research Day.
  • Ella Bok, graduate student in the Moffitt-USF Cancer Biology Ph.D. Program, in the Karreth lab, won a 2020 Outstanding Research Accomplishment Award from Moffitt's PhD program.

January 2021

  • New Publication: Aziz Aiderus, PhD, Post-doctoral Fellow in the M. Mann Lab, Ana M. Contreras-Sandoval, PhD, Post-doctoral Fellow in the M. Mann Lab, & Amanda Meshey, PhD Graduate Student in the M. Mann Lab, published a joint first co-authored publication in Cancers, entitled “Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation”. This collaborative work from senior co-authors Karen Mann, PhD and Michael Mann, PhD, Demonstrates there are oncogene independent routes to drive cancer development! This manuscript uncovers the critical role of tumor suppressor genes (both new and known) in the initiation and progression of multiple solid cancers.
  • New Trainee: Allison Bahr joined the team as a Research Associate supporting the Puerto Rico Bio-Bank. Allison is a recent University of Florida graduate who double-majored in Microbiology and Spanish.
  • New Appointment: Doug Cress, PhD, was appointed as Moffitt’s Institutional Research Integrity Officer.
  • New Appointment: Michael Mann, PhD, joins the Editorial Board of Biomolecules as a Special Topics Editor. His first project as Guest Editor is developing a multi-disciplinary Cancer Genetics issue launching later in 2021.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Stewart PA, Welsh EA, Fang B, Izumi V, Mesa T, Zhang C, Yoder S, Zhang G, Cen L, Pettersson F, Zhang Y, Chen Z, Cheng CH, Thapa R, Thompson Z, Avedon M, Wloch M, Fournier M, Fellows KM, Francis JM, Saller JJ, Boyle TA, Chen YA, Haura EB, Teer JK, Eschrich SA, Koomen JM. Managing a Large-Scale Multiomics Project: A Team Science Case Study in Proteogenomics. Methods Mol Biol. 2021;2194:187–221. PMID: 32926368

December 2020

  • Apis Assay Technologies has signed a master collaboration agreement with Tampa, Florida-based Moffitt Cancer Center to determine the suitability of TROLL–2 and TROLL–3 long non-coding RNAs (lncRNA) as predictive biomarkers for cancer progression.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Fang B, Izumi V, Rix LLR, Welsh E, Pike I, Reuther GW, Haura EB, Rix U, Koomen JM. Lowering Sample Requirements to Study Tyrosine Kinase Signaling Using Phosphoproteomics with the TMT Calibrator Approach. Proteomics.2020 Dec;20(24):e2000116. Epub 2020 Sep 30. PMID: 32865326.
  • New Publication: Doug Cress, PhD, lead Karthikeyan SK, Gimbrone NT, Percy TR, Cress WD. Loss of cellular identity in common pre-clinical models of serine threonine kinase 11 (Liver kinase B1) loss. Cancer Treat Res Commun. PubMed PMID: 33338855.
  • New Publication: Olga Vera, PhD, Postdoctoral Fellow, and Neel Jasani, Graduate Student, in the Karreth lab published a review article titled "Long Non-Coding RNAs in Melanoma Development and Biology" in Proceedings of the Singapore National Academy of Sciences.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Hajiran A, Chakiryan N, Aydin AM, Zemp L, Nguyen J, Laborde JM, Chahoud J, Spiess PE, Zaman S, Falasiri S, Fournier M, Teer JK, Dhillon J, McCarthy S, Moran-Segura C, Katende EN, Sexton WJ, Koomen JM, Mulé J, Kim Y, Manley B. Reconnaissance of tumor immune microenvironment spatial heterogeneity in metastatic renal cell carcinoma and correlation with immunotherapy response. Clin Exp Immunol. 2020 Dec 21. Online ahead of print. PMID: 33346915.

November 2020

  • Ana Gomes, PhD contributed with an opinion piece for Cancer Cell - Voices on the impact of COVID–19 Pandemic on cancer research. Dr. Gomes reflects on the challenges of starting a lab as a junior faculty in the middle of the COVID–19 pandemic.
  • New Publication: Gary W. Reuther, PhD and members of Ken Wright’s lab (Immunology) published a perspective on “Metabolic Vulnerabilities and Epigenetic Dysregulation in Myeloproliferative Neoplasms”. Front Immunol. 2020 Nov 30. PMID: 33329600.
  • Doug Cress, PhD, served as a co-host of the “Footsteps to Funding” event, in support of training for GMAP Region 2
  • Doug Cress, PhD, gave a virtual seminar at the University of Puerto Rico entitled, “Molecular Drivers in Lung Cancer”
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Garg SK, Welsh EA, Fang B, Hernandez YI, Rose T, Gray J, Koomen JM, Berglund A, Mulé JJ, Markowitz J. Multi-Omics and Informatics Analysis of FFPE Tissues Derived from Melanoma Patients with Long/Short Responses to Anti-PD1 Therapy Reveals Pathways of Response. Cancers (Basel).2020 Nov 26;12(12):3515. doi: 10.3390/cancers12123515. PMID: 33255891.
  • Mark Alexandrow, PhD, received Award from Adolescent and Young Adult Program (AYA) at Moffitt for a project titled: “Assessing the anti-tumor efficacy of first-in-class human CMG helicase inhibitors in pre-clinical models of osteosarcoma”. Drs. Mark Alexandrow and Damon Reed are co-PIs.
  • Trainee Milestone: Koji Nakamura, PhD, former Postdoctoral Fellow left the Karreth lab and returned to his native Japan where he assumed an Assistant Professor position at Osaka University.

October 2020

  • New Grant Award: Jennifer Binning, PhD received a pilot Award from the Center For Immunization And Infection Research In Cancer (CIIRC) for Moffitt Faculty Conducting Research in Immunizations and Infection-Related Cancers.
  • New Patent: Mark G. Alexandrow, PhD is named inventor for Provisional Patent submission #63/087,415 “CMG Helicase Inhibitors for the Treatment of Cancers”.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Darville LNF, Cline JK, Rozmeski C, Martinez YC, Rich S, Eschrich SA, Egan KM, Yaghjyan L, Koomen JM. LC-HRMS of derivatized urinary estrogens and estrogen metabolites in postmenopausal women. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Oct 1;1154:122288. Epub 2020 Jul 29. PMID: 32769047.
  • New Publication: Napoli M, Li X, Ackerman HD, Barranikov I, Pisegna MA, Bedrodian I, Mitsch J, Quinlan P, Thompson A, Rajapakshe K, Coarfa C, Gunaratne P, Marchion D, Magliocco A, Tsai KY, Flores ER. Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation. Nat Commun. 2020 Oct 14;11(1):5156. PMID: 33056990
  • New Publication: Nguyen TN, Rajapakshe K, Nicholas C, Tordesillas L, Ehli EA, Davis CM, Coarfa C, Flores ER, Dickinson SE, Curiel-Lewandrowski C, Tsai KY. Integrative transcriptomic analysis for linking acute stress responses to squamous cell carcinoma development. Sci Rep. 2020 Oct 14;10(1):17209. PMID: 33057049
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Taylor NJ, Gaynanova I, Eschrich SA, Welsh EA, Garrett TJ, Beecher C, Sharma R, Koomen JM, Smalley KSM, Messina JL, Kanetsky PA. Metabolomics of primary cutaneous melanoma and matched adjacent extratumoral microenvironment. PLoS One. 2020 Oct 27;15(10):e0240849. PMID: 33108391.
  • Trainee Milestone: Nicol Mecozzi, visiting student in the Karreth lab, defended her Master's thesis in Cell and Molecular Biology at the University of Pisa in Pisa, Italy.

September 2020

  • Trainee Milestone: Marco Napoli, PhD in the Flores Lab is promoted to Research Scientist II
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Zhang C, Smalley I, Emmons MF, Sharma R, Izumi V, Messina J, Koomen JM, Pasquale EB, Forsyth PA, Smalley KSM. Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor‒Resistant Melanoma. J Invest Dermatol. 2020 Sep 2:S0022–202X(20)32047–9. Online ahead of print. PMID: 32890629.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Hamaidi I, Zhang L, Kim N, Wang MH, Iclozan C, Fang B, Liu M, Koomen JM, Berglund AE, Yoder SJ, Yao J, Engelman RW, Creelan BC, Conejo-Garcia JR, Antonia SJ, Mulé JJ, Kim S. Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells. Cell Metab. 2020 Sep 1;32(3):420–436.e12. doi: 10.1016/j.cmet.2020.07.008. Epub 2020 Aug 7. PMID: 32768387.

August 2020

  • Karen Mann, PhD, presented at the 2020 PanCAN Virtual Scientific Summit at platform presentation entitled, “The Splicing Factor RBFOX2 Drives Pancreatic Cancer Progression”.
  • New Trainee: Suehelay Acevedo, PhD, joins the Flores Lab as a postdoctoral fellow.
  • New Trainee: Aleah Masucci joined the team as a Covid–19 SPARK Intern.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK. Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. Blood. 2020 Aug 13;136(7):857–870. doi: 10.1182/blood.2019003257. PMID: 32403132.
  • New Grant Award: Florian Karreth, PhD, and Dennis Adeegbe, PhD, (Department of Immunology) were awarded a Moffitt Team Science Award for their proposal to generate iGEMMs, chimeric melanoma mouse models to study immune cell-specific gene functions.
  • New Grant Award: Florian Karreth, PhD, was awarded a Pilot Award from the Donald A. Adam Melanoma and Skin Cancer Center of Excellence.

July 2020

  • New Publication: Jinesh GG, Napoli M, Ackerman HD, Raulji PM, Montey N, Flores ER, Brohl AS. Regulation of MYO18B mRNA by a network of C19MC miRNA–520G, IFN-γ, CEBPB, p53 and bFGF in hepatocellular carcinoma. Sci Rep. 2020 Jul 23;10(1):12371. PMID: 32704163
  • Doug Cress, PhD, participated in an NCI Grant Review Panel, U54 Partnerships for Cancer Health Equity.
  • New Grant Award: Michael Mann, PhD, received a Pilot Award from the Donald A. Adam Melanoma and Skin Cancer Center of Excellence for Projects in Non-Melanoma Skin Cancer.
  • New Appointment: Michael Mann, PhD, joins Cancers as a Review Board Member.

June 2020

  • New Faculty: Ana Gomes, PhD joins the department as an Assistant Member. Welcome Dr. Gomes!
  • Beyond our Walls: On June 10, the Department of Molecular Oncology took the time to read and reflect on the following in solidarity with inclusion and racial justice in Basic and Cancer Science: I could have been George Floyd - many times. Rob Winn, MD – The Cancer LetterI could have been George Floyd, too. Otis Brawley, MD, MACP, FASCO, FACE – The Cancer LetterWhite Academia: Do Better. The Faculty - Medium, Systemic racism: science must listen, learn and change - Nature, and Concrete Steps for Recruiting, Supporting, and Advancing Underrepresented Minoritized Scientists
  • New Grant Award: Gary Reuther, PhD and Nicholas Lawrence, PhD (Drug Discovery) and Ernst Schönbrunn, PhD (Drug Discovery), were awarded funding for three years from the State of Florida Bankhead-Coley Cancer Research program for their project entitled “Novel monovalent and bivalent JAK2 inhibitors for targeted MPN and cancer therapies”.
  • New Grant Award: Jiandong Chen, PhD, Faculty Mark Ji, PhD (Drug Discovery) and Gary Daughdrill, PhD (USF Cell Biology, Microbiology and Molecular Biology), were awarded funding for three years from the State of Florida Bankhead-Coley Cancer Research program for their project entitled "Discovery of p53 Inhibitors for Reducing Toxicity of Chemotherapy."
  • New Publication: Mark G. Alexandrow, PhD, together with a diverse set of Moffitt Faculty, published a new paper "An Evolutionary Framework for Treating Pediatric Sarcomas" in Cancer doi: 10.1002/cncr.32777. PMID: 32176331.
  • Qingliang Li ArticleNew Publication: Qingling Li, PhD, Postdoctoral Fellow in the Chen Lab, published a new paper in Oncogene. "Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity." Qingliang Li, Rezaul M. Karim, Mo Cheng, Mousumi Das, Lihong Chen, Chen Zhang, Harshani R. Lawrence, Gary Daughdrill, Ernst Schonbrunn, Haitao Ji, and Jiandong Chen. (2020). In press. doi: 10.1038/s41388–020–1344-y
  • New Publication: Michael B. Mann, PhD, and Justin Y. Newberg, PhD, alumnus Applied Research Scientist, contributed to a paper published in Journal of Investigative Dermatologyby directed by Kenneth Y. Tsai, MD, PhD (Tumor Biology & Anatomic Pathology). PMID: 32553564.
  • New Publication: Qingling Huang, PhD, Postdoctoral Fellow in the Chen Lab, published a new paper in EMBO J. “MDMX inhibits CK1α kinase activity and stimulates Wnt signaling”. Qingling Huang, Lihong Chen, Ernst Schonbrunn, Jiandong Chen. (2020). DOI: 10.15252/embj.2020104410. PMID: 32511789.
  • Faculty in the Spotlight: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, mentored Proteomics & Metabolomics Core staff for their presentations at the American Society for Mass Spectrometry Annual Conference Reboot, which is our first online-only virtual conference.
  • Trainee Milestone: Trent Percy, an undergraduate student completed his Bachelor’s Degree at USF and will begin studies Arkansas College of Osteopathic Medicine in the fall of 2020.

May 2020

  • Faculty in the Spotlight: Doug Cress, PhD, was quoted in an Endeavor article: Making the Most Impact to Save the Future.
  • Trainee Milestone: Santhosh Kumar Karthikeyan, a graduate student in Dr. Cress’ lab completed his Bioinformatics Master’s Program and will begin a PhD graduate program at the University of Alabama in the fall of 2020.
  • New Grant Award: John Koomen, PhD and Theresa Boyle, MD, PhD (Anatomic Pathology & Clinical Pathology) started a new MPI project to compare multiple lung cancer metastases in patients to examine tumor biology in terminal disease to generate additional treatment strategies, which is funded by a 3 year Bankhead Coley Discovery Science Award.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, worked with Victoria Izumi (Core research specialist) and Bin Fang (Core manager) to support a project led by Keiran Smalley, PhD (Tumor Biology & Cutaneous Oncology) examining protein biomarkers associated with prognosis in melanoma brain metastases. Smalley I, Law V, Wyatt C, Evernden B, Fang B, Koomen JM, Welsh EA, Macaulay RJB, Forsyth PA, Smalley KSM. “Proteomic Analysis of CSF from Patients with Leptomeningeal Melanoma Metastases Identifies Signatures Associated with Disease Progression and Therapeutic Resistance.” Clin Cancer Res. 2020 May 1;26(9):2163–2175. PMID: 31924735.
  • New Publication: John Koomen, PhD, Proteomics & Metabolomics Scientific Director, contributed to a publication in metabolomics, which indicates continuing development of metabolomics services at Moffitt and additional productivity for our ongoing metabolomics collaborations with Tim Garrett, PhD, an investigator in the South East Center for Integrated Metabolomics at the University of Florida. Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin C, Alontaga AY, McDaniel J, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence H, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha A, Cleveland JL, Epling-Burnette PK. Cereblon Harnesses Myc-Dependent Bioenergetics and Activity of CD8+ T lymphocytes. Blood. 2020 May 13:blood.2019003257. PMID: 32403132.

April 2020

  • Bui Cancer ArticleNew Publication: Ngoc Bui, PhD, alumnus Postdoctoral Fellow in the Flores Lab, published a paper in Cancer Research: Spatiotemporal regulation of ∆Np63 by TGFβ-regulated miRNAs is essential for cancer metastasis. Bui NHB, Napoli M, Davis AJ, Abbas HA, Rajapakshe K, Coarfa C, Flores ER. Cancer Res. 2020 Apr 20:canres.2733.2019. doi: 10.1158/0008–5472.CAN–19–2733. PMID: 32312834.
  • New Publication: Mark G. Alexandrow, PhD, and Damon R. Reed, MD, Medical Oncology and Program Leader of the Adolescent Young Adult Program, were co-corresponding authors of a paper in BioEssays: Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer. doi: 10.1002/bies.201900218. PMID: 32080866.