Manipulating Super-Enhancers to Thwart Drug Resistance in Lymphoma
Exploiting ‘BRCAness’ in Homologous Repair Competent Tumors
Disabling Oncogenic β-catenin
Chemical Biology Reveals Off-Target Drug Repurposing
The Molecular Medicine (MM) Program integrates chemical biology and systems biology technologies to develop new therapeutic approaches for the treatment of cancer. Along with research in chemistry, drug discovery and clinical trials, the MM Program includes members interrogating signaling pathways that regulate cell proliferation and survival to identify new targets for cancer therapeutics. The inclusion of basic scientists, chemists, and clinical researchers creates unique opportunities to rapidly translate novel strategies into the clinic, while conversely also increasing the flow of observations from the clinic back to the laboratory for mechanistic testing.
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